Exhilaratives are a class of medicine especially of the Arab physicians, although the original Laetificans (Latin for Happy or Cheerful), credited to Galen, shows the ancient Greeks were the first to use this class of medicine. However, Unani has a number of elegant compounds used as Exhilarants, often containing gems, and still uses such compounds today.

Exhilaratives are medicines that promote a feeling of Joy or Cheerfulness. These medicines tend to uplift the Spirits, move Qi, support the Heart and gladden the Spirit.

Ayurveda has the Hridya group of drugs, those that promote Cheerfulness:

Mangifera indica, Spondias pinnata, Artocarpus lakucha, Pongamia glabra, Oxalis cornuculata, Rumex vesicarius, Zizyphus oenoplia, Ziziphus jujuba, Punica granatum, Citrus acida

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Compounds

Principle formulas used include:
Electuary of Aloeswood
Powder of Ambergris
Aromatic Musk Compound

Syrup of Borage
Syrup of Borage juice
Conserve of Borage Flowers
The Exhilarative Syrup (Laurent)
Tincture of Life (Mynsichts)
Powder of Happiness (Letificans)
Letificans Almansoris (Rhasis)
Letificans Electuary of Filius Zacharia
Electuary of Aloeswood (Diaxyloaloes) (Mesue)
Royal Confection of Kermes (Mesue)
Powder of Ambergris (Diambra) (Mesue)
Powder of Rosemary Compound (Dianthos) (Nicholas)
Cooling Pearl Powder (Diamargariton Frigidum)
Restorative of Nicholas (Pleres Arconticon) (Nicholas)
Confection of Hyacinth (Confectio de Hyacintho)
Electuary of Gems (Mesue)
Electuary of Reschidi (Unani)
Letificans Electuary (Unani)
Letificans Cooling Electuary (Unani)
Medicine to Defend the Base from all Danger
The Great Electuary
Pills of Lapis Lazuli 1 (Mesue)
Safoof e Jawahar Mohra (Precious Defender Powder)

Purgatives
Electuary of Senna (Nicholas)
Hiera Logadi
Hiera Pachi, or Hiera Archigenis
Pills of Lapis Lazuli 1 (Mesue)
Pills of Lapis Armenius
Arabian Pills (Nicholas)

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Special Formula

Electuary Letificans of Filius Zacharia
    Rose                          2 drams
    Cyperus                    3 drams
    Clove
    Mastic
    Aloeswood
    Spikenard
    Asarum                     1 ½ drams
    Cinnamon
    Saffron
    Balm
    Clove Basil seed
    Pearl
    Indian leaf
    Mace
    Lesser Cardamon 
    Greater Cardamon
    Nutmeg
    Citron peel
    Gallia Moschata
    Zedoary
    Doronicum
    Basil                           1 dram
    Musk                          ¼ dram
Form a confection with Honey of Belleric and Emblic Myrobalan, 4 times the weight of the powders.
“Confers blessedness, beauty, complexion, improves odor, improves digestion, retards grey hair”. (De Morbis Internis Curandis, Mesue, 1551)